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TET2 (N2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212098Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212098Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to TET2. TET2 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) . 5-hydroxymethylcytosine may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. TET2 plays an important role in myelopoiesis, and defects in TET2 gene have been associated with several myeloproliferative disorders.
Product Name Alternative
Anti Methylcytosine dioxygenase TET2 antibody, anti KIAA1546 antibody
UniProt
Q4JK59
Reactivity
Mouse
Immunogen
N-terminal region of mouse TET2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
224
References & Citations
Da Silva, Rodrigo A. et al. Laminar shear stress-provoked cytoskeletal changes are mediated by epigenetic reprogramming of TIMP1 in human primary smooth muscle cells J Cell Physiol, 234, 6382-6396 (2019)
Pubmed id
30238981
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse TET2.
Tested Applications
ChIP, IF, IP, WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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