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GRIN1 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212092Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212092Size:100 µL
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Description
Rabbit polyclonal to GRIN1. Glutamate receptor ionotropic, NMDA 1 (GRIN1) belongs to the glutamate-gated ion channel (TC 1.A.10.1) family and the NR1/GRIN1 subfamily. GRIN1 is an NMDA receptor subtype of glutamategated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. GRIN1 is mediated by glycine, and this protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. GRIN1 mediates neuronal functions in glutamate neurotransmission, and it is also involved in the cell surface targeting of NMDA receptors.
Product Name Alternative
Anti Glutamate receptor ionotropic antibody, anti NMDA 1 antibody, anti GluN1 antibody, anti Glutamate [NMDA] receptor subunit zeta-1 N-methyl-D-aspartate receptor subunit NR1 antibody, anti NMD-R1 antibody, anti NMDAR1 antibody
UniProt
Q05586
Reactivity
Human, Mouse
Immunogen
N-terminal region of human GRIN1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics, Neuroscience
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
105
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human GRIN1.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q05586

Glutamate receptor ionotropic, NMDA 1

NMDZ1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q05586
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GRIN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GluN1
EC number
—
Processing
Precursor
Secondary accessions
A6NLK7, A6NLR1, C9K0X1, P35437, Q12867, Q12868, Q5VSF3, Q5VSF4, Q5VSF5, Q5VSF6, Q5VSF7, Q5VSF8, Q9UPF8, Q9UPF9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-bindingZinc

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

Disease

Disease variantEpilepsyIntellectual disability

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Ion channelLigand-gated ion channelReceptor

Biological process

Ion transportTransport

Domain

SignalTransmembraneTransmembrane helix

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