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KAISO (N2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212075Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212075Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to KAISO. KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulator with bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in the consensus sequence 5-CGCG-3 and also binds to the non-methylated consensus sequence 5-CTGCNA-3. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. In contrast, KAISO may also activate transcription of a subset of target genes by the recruitment of CTNND2.
Product Name Alternative
Anti ZBTB33 antibody, anti ZNF348 antibody, anti Zinc finger and BTB domain-containing protein 33 antibody
UniProt
Q8BN78
Reactivity
Human, Mouse
Immunogen
N-terminal region of mouse KAISO
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics, Neuroscience, Signaling Pathways, Wnt
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
74
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse KAISO.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q8BN78

Transcriptional regulator Kaiso

KAISO_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8BN78
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Zbtb33
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8C226, Q9WTZ7
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Reference proteome

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulationWnt signaling pathway

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