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IKZF3 (C1) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212067Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212067Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to IKZF3. Zinc finger protein Aiolos (IKZF3) belongs to the Ikaros C2H2-type zinc-finger protein family. IKZF3 is a transcription factor that plays an important role in the regulation of lymphocyte differentiation. IKZF3 plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Additionally, IKZF3 is involved in regulating BCL2 expression and controlling apoptosis in Tcells in an IL2-dependent manner.
Product Name Alternative
Anti Zinc finger protein Aiolos antibody, anti Ikaros family zinc finger protein 3 antibody, anti ZNFN1A3 antibody
UniProt
Q9UKT9
Reactivity
Human
Immunogen
C-terminal region of human IKZF3
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
58
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human IKZF3.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9UKT9

Zinc finger protein Aiolos

IKZF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKT9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IKZF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DVV5, Q69BL6, Q69BL7, Q69BL8, Q69BL9, Q69BM0, Q69BM1, Q69BM2, Q69BM3, Q69BM5, Q8N574, Q8WWQ9, Q8WWR0, Q8WWR1, Q8WWR2, Q8WWR3
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

B-cell activationTranscriptionTranscription regulation

Cellular component

CytoplasmNucleus

Disease

Disease variant

Molecular function

DNA-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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