Products for Research Use Only
RegisterLogin

RPS6KA5 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212038Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18212038Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Rabbit polyclonal to RPS6KA5. Ribosomal protein S6 kinase alpha-5 (RPS6KA5) belongs to the protein kinase superfamily, the AGC Ser/Thr protein kinase family, and the S6 kinase subfamily. RPS6KA5 is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. RPS6KA5 phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Additionally, RPS6KA5 plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.
Product Name Alternative
Anti Ribosomal protein S6 kinase alpha-5 antibody, anti S6K-alpha-5 antibody, anti 90 kDa ribosomal protein S6 kinase 5 antibody, anti Nuclear mitogen-and stress-activated protein kinase 1 antibody, anti RSK-like protein kinase antibody, anti RSKL antibody, anti MSK1 antibody
UniProt
O75582
Reactivity
Human
Immunogen
N-terminal region of human RPS6KA5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
90
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human RPS6KA5.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · O75582

Ribosomal protein S6 kinase alpha-5

KS6A5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75582
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RPS6KA5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
S6K-alpha-5
EC number
2.7.11.1
Processing
—
Secondary accessions
B7Z2Y5, O95316, Q96AF7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

Biological process

Inflammatory responseStress response

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

Domain

Repeat

Related Products

CatalogName
GTR18035471-01RPS6KA5 Rabbit Polyclonal Antibody
GTR18681601-01RPS6KA5 Rabbit Polyclonal Antibody
GTR18091361RPS6KA5 Rabbit Polyclonal Antibody
GTR18080758-01RPS6KA5 Rabbit Polyclonal Antibody
GTR17691204MSK1/RPS6KA5 Rabbit Polyclonal Antibody
GTR18295467-01RPS6KA5 polyclonal antibody
GTR18567291MSK1/RPS6KA5 Rabbit Polyclonal Antibody (FITC)
GTR18727312MSK1/RPS6KA5 Rabbit Polyclonal Antibody (Fluoro488)
GTR18727290MSK1/RPS6KA5 Rabbit Polyclonal Antibody (Fluoro594)
GTR18567289MSK1/RPS6KA5 Rabbit Polyclonal Antibody (HRP)

Alternative Products

CatalogName
MBS8506977-01RPS6KA5 Antibody (Rabbit Polyclonal)
E10G10195RPS6KA5 Rabbit Polyclonal Antibody
AP32045PU-NMSK1 (RPS6KA5) Rabbit Polyclonal Antibody
E10G33161Mouse Rps6ka5 Rabbit Polyclonal Antibody
TA322708Anti-RPS6KA5 Rabbit Polyclonal Antibody
NBP1-82618Rabbit Polyclonal MSK1/RPS6KA5 Antibody
E-AB-92667-01RPS6KA5 Polyclonal Antibody

Popular Products