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Dehydroindapamide

CAT: 0804-HY-W420344-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W420344-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dehydroindapamide is the indole form of Indapamide. Dehydroindapamide standard can be used to quantitatively measure the Indapamide turnover rate by CYP3A4, which was approximately 10-fold higher than that of Indoline (HY-Y0788), and slightly enhanced affinity for CYP3A4[1].
CAS Number
63968-75-2
UNSPSC
12352005
Hazard Statement
H361-H362
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dehydroindapamide.html
Smiles
O=C(C1=CC=C(C(S(=O)(N)=O)=C1)Cl)NN2C3=C(C=C2C)C=CC=C3
Molecular Formula
C16H14ClN3O3S
Molecular Weight
363.82
Precautions
P260-P263-P264-P270-P280-P405-P501
References & Citations
[1]Sun H, et al. Dehydrogenation of the indoline-containing drug 4-chloro-N- (2-methyl-1-indolinyl) -3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions. Drug Metab Dispos. 2009 Mar;37 (3) :672-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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