Sapropterin (dihydrochloride) (Standard)

Sapropterin (dihydrochloride) (Standard)

• CAS Number: 69056-38-8
• UNSPSC Description: Sapropterin (dihydrochloride) (Standard) is the analytical standard of Sapropterin (dihydrochloride). This product is intended for research and analytical applications. Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU)[1][2].
• Target Antigen: Others
• Type: Reference Standards
• Related Pathways: Others
• Field of Research: Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/sapropterin-dihydrochloride-standard.html
• Purity: 99.96
• Smiles: O=C1N=C(N)NC2=C1N[C@@H]([C@@H](O)[C@@H](O)C)CN2.[H]Cl.[H]Cl
• Molecular Weight: 314.17
• References & Citations: [1]Sanford M, et al. Sapropterin: a review of its use in the treatment of primary hyperphenylalaninaemia. Drugs. 2009;69(4):461-76. |[2]Schmitz K, et al. Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice. Neurotherapeutics. 2021 Jul;18(3):1862-1879.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)