Products for Research Use Only

KDM5B (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210396Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210396Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to KDM5B.Lysine (K) -specific demethylase 5B (KDM5B) is a ubiquitously expressed nuclear protein. It is ahistone demethylase that specifically demethylates Lys-4 of histone H3. It can demethylatetrimethylated, dimethylated, and monomethylated Lys-4. It acts as a transcriptional corepressor forFOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressorgenes such as BRAC1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor formelanoma.
Product Name Alternative
Anti-KDM5B antibody, anti-CT31 antibody, anti-FLJ10538 antibody, anti-FLJ12491 antibody, anti-FLJ16281 antibody, anti-FLJ23670 antibody, anti-JARID1B. PLU1 antibody, anti-PLU1 antibody, anti-PUT1 antibody, anti-RBBP2H1 antibody, anti-Cancer antibody, anti-testis antigen 31 antibody, anti-Histone demethylase JARID1B antibody, anti-Jumonji antibody, anti-ARID domaincontaining protein 1B antibody, anti-Retinoblastomabinding protein 2 homolog 1 antibody
UniProt
Q9UGL1
Reactivity
Human, Mouse
Immunogen
N-terminal region of human KDM5B
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
176
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9UGL1

Lysine-specific demethylase 5B

KDM5B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UGL1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDM5B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.11.67
Processing
—
Secondary accessions
O95811, Q15752, Q9Y3Q5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsTranscriptionTranscription regulation

Molecular function

Chromatin regulatorDioxygenaseOxidoreductaseRepressor

Disease

Disease variantIntellectual disability

Ligand

IronMetal-bindingZinc

Cellular component

Nucleus

Domain

RepeatZinc-finger

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