Products for Research Use Only

PTPN22 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210365Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210365Size:100 µL
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Description
Rabbit polyclonal to PTPN22.Tyrosine-protein phosphatase non-receptor type 22 (PTPN22) belongs to the protein-tyrosinephosphatase family, non-receptor class 4 subfamily. PTPN22 may play a role in regulating thefunction of Cbl and its associated protein kinases. PTPN22 also acts as a negative regulator of T-cellreceptor (TCR) signaling. PTPN22 dephosphorylates and inactivates the SRC family kinases. Defectsin PTPN22 are a cause of susceptibility to systemic lupus erythematosus (SLE) .
Product Name Alternative
Anti-PTPN22 antibody, anti-Tyrosineprotein phosphatase nonreceptor type 22 antibody, anti-Hematopoietic cell proteintyrosine phosphatase 70ZPEP antibody, anti-Lymphoid phosphatase antibody, anti-LyP antibody, anti-PESTdomain phosphatase antibody, anti-PEP antibody, anti-PTPN8 antibody
UniProt
Q9Y2R2
Reactivity
Human
Immunogen
N-terminal region of human PTPN22
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
92
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9Y2R2

Tyrosine-protein phosphatase non-receptor type 22

PTN22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y2R2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTPN22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.48
Processing
—
Secondary accessions
A0N0K6, B1ALC8, D4NZ71, E9PLD8, E9PPI1, O95063, O95064, Q6IPX8, Q8WVM1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AutophagyImmunityLipid metabolism

Cellular component

Cytoplasm

Disease

Diabetes mellitusDisease variantSystemic lupus erythematosus

PTM

Disulfide bondPhosphoprotein

Molecular function

HydrolaseProtein phosphatase

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