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TLK1 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210355Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210355Size:100 µL
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Description
Rabbit polyclonal to TLK1.Serine/threonine-protein kinase tousled-like 1 (TLK1) belongs to the protein kinase superfamily, Ser/Thr protein kinase family. TLK1 can be rapidly and transiently inhibited by phosphorylationfollowing the generation of DNA double-stranded breaks (DSBs) during S-phase. This event is cellcycle checkpoint and A-pathway dependent and appears to regulate processes involved inchromatin assembly. TLK1 exists in several isoforms, and Isoform 3 protects the cells from theionizing radiation by faciliting the repair of DSBs.
Product Name Alternative
Anti-TLK1 antibody, anti-Serine antibody, anti-threonineprotein kinase tousledlike 1 antibody, anti-PKUbeta antibody, anti-Tousledlike kinase 1 antibody, anti-KIAA0137 antibody
UniProt
Q9UKI8
Reactivity
Human, Mouse
Immunogen
N-terminal region of human TLK1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
87
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9UKI8

Serine/threonine-protein kinase tousled-like 1

TLK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKI8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TLK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
B3KR15, B4DX87, Q14150, Q8N591, Q9NYH2, Q9Y4F6
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleDNA damage

Molecular function

Chromatin regulatorKinaseSerine/threonine-protein kinaseTransferase

Domain

Coiled coil

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

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