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MMP20 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210339Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210339Size:100 µL
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Description
Rabbit polyclonal to MMP20.MMP20 is a matrix mellanoproteinase belonging to the peptidase M10A family. It degradesamelogenin, the major protein component of the enamel matrix and two of the macromoleculescharacterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP) . MMP20 may play a central role in tooth enamel formation. A mutation in the gene resultingin premature termination of the encoded protein has been associated with amelogenesis imperfecta.
Product Name Alternative
Anti-MMP20 antibody, anti-Matrix metalloproteinase20 antibody, anti-MMP20 antibody, anti-Enamel metalloproteinase antibody, anti-Enamelysin antibody
UniProt
O60882
Reactivity
Human
Immunogen
C-terminal region of human MMP20
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Dilution
WB:1:500-1:1000
Purity
Affinity purification
Molecular Weight
54
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · O60882

Matrix metalloproteinase-20

MMP20_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60882
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MMP20
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MMP-20
EC number
3.4.24.-
Processing
Precursor
Secondary accessions
Q6DKT9
Protein keywords

Technical term

3D-structureReference proteome

Disease

Amelogenesis imperfecta

PTM

Autocatalytic cleavageDisulfide bondZymogen

Ligand

CalciumMetal-bindingZinc

Cellular component

Extracellular matrixSecreted

Molecular function

HydrolaseMetalloproteaseProtease

Domain

RepeatSignal

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