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SOCS6 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210337Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210337Size:100 µL
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Description
Rabbit polyclonal to SOCS6.Suppressor of cytokine signaling 6 (SOCS6) is a member of the SOCS family proteins that form partof a classical negative feedback system that regulates cytokine signal transduction. SOCS6 may be asubstrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomaldegradation of target proteins. SOCS6 regulates the degradation of the tyrosine-phosphorylated KITreceptor by ubiquitination.
Product Name Alternative
Anti-SOCS6 antibody, anti-Suppressor of cytokine signaling 6 antibody, anti-SOCS6 antibody, anti-Cytokineinducible SH2 protein 4 antibody, anti-CIS4 antibody, anti-Suppressor of cytokine signaling 4 antibody, anti-SOCS4 antibody, anti-CIS4 antibody, anti-SOCS4 antibody
UniProt
O14544
Reactivity
Human, Mouse
Immunogen
C-terminal region of human SOCS6
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
60
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · O14544

Suppressor of cytokine signaling 6

SOCS6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14544
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOCS6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SOCS-6
EC number
—
Processing
—
Secondary accessions
Q8WUM3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Growth regulationUbl conjugation pathway

Domain

SH2 domain

Molecular function

Signal transduction inhibitor

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