Products for Research Use Only

MLK1 (M) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210336Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210336Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to MLK1.Mixed lineage kinase 1 (MLK1) is also known as Mitogen-activated protein kinase kinase kinase 9 (MAP3K9), which is a serine/threonine kinase acting as an essential component of the MAP kinasesignal transduction pathway. MLK1 plays an important role in the cascades of cellular responsesevoked by changes in the environment. Once activated, MLK1 acts as an upstream activator of theMKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 andMAP2K7/MKK7, which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stressresponse via activator protein-1 (JUN) and GATA4 transcription factors. MLK1 also plays a role inmitochondrial apoptosis signaling pathway, including the release cytochrome c.
Product Name Alternative
Anti-MLK1 antibody, anti-Mitogenactivated protein kinase kinase kinase 9 antibody, anti-Mixed lineage kinase 1 antibody, anti-PRKE1 antibody, anti-MAP3K9 antibody
UniProt
P80192
Reactivity
Human, Mouse
Immunogen
Middle region of human MLK1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
122
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3