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NEDD5 (C1) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210297Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210297Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to NEDD5.Septin-2 (NEDD5) is a filament-forming cytoskeletal GTPase that belongs to the septin family. It isrequired for normal organization of the actin cytoskeleton. NEDD5 plays a role in the biogenesis ofpolarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitatingefficient vesicle transport. NEDD5 is required for the progression through mitosis. During anaphase, NEDD5 may be required for chromosome segregation and spindle elongation. NEDD5 plays a role inciliogenesis and collective cell movements. It may also play a role in the internalization of 2intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Product Name Alternative
Anti-NEDD5 antibody, anti-Septin2 antibody, anti-Neural precursor cell expressed developmentally downregulated protein 5 antibody, anti-NEDD5 antibody, anti-DIFF6 antibody, anti- KIAA0158 antibody
UniProt
Q15019
Reactivity
Human
Immunogen
C-terminal region of human NEDD5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Dilution
WB:1:500-1:3000
Purity
Affinity purification
Molecular Weight
41
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q15019

Septin-2

SEPT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15019
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SEPTIN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DGE8, Q14132, Q53QU3, Q8IUK9, Q96CB0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionDifferentiationMitosisSpermatogenesis

Cellular component

Cell membraneCell projectionCentromereChromosomeCiliumCytoplasmCytoskeletonFlagellumKinetochoreMembrane

Ligand

GTP-bindingNucleotide-binding

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