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CCR5 (M) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210267Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210267Size:100 µL
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Description
Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22) .
Product Name Alternative
Anti-CCR5 antibody, anti-CC chemokine receptor type 5 antibody, anti-CC CKR5 antibody, anti-CCCKR5 antibody, anti-CCR5 antibody, anti-CCR5 antibody, anti-CHEMR13 antibody, anti-HIV1 fusion coreceptor antibody, anti-CD195 antibody, anti-CMKBR5 antibody
UniProt
P51681
Reactivity
Human, Mouse
Immunogen
Middle region of human CCR5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
41
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · P51681

C-C chemokine receptor type 5

CCR5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51681
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCR5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
C-C CKR-5, CC-CKR-5, CCR-5, CCR5
EC number
—
Processing
—
Secondary accessions
O14692, O14693, O14695, O14696, O14697, O14698, O14699, O14700, O14701, O14702, O14703, O14704, O14705, O14706, O14707, O14708, O15538, Q9UPA4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoproteinLipoproteinPalmitatePhosphoproteinSulfation

Molecular function

G protein-coupled receptorHost cell receptor for virus entryReceptorTransducer

Biological process

Host-virus interaction

Domain

TransmembraneTransmembrane helix

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