Products for Research Use Only

CBL (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210237Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210237Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to CBL.E3 ubiquitin-protein ligase CBL is an adapter protein that functions as a negative regulator of manysignaling pathways that are triggered by activation of cell surface receptors. It acts as an E3 ubiquitinproteinligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and thentransfers it to substrates promoting their degradation by the proteasome. CBL plays an important rolein the regulation of osteoblast differentiation and apoptosis and is essential for osteoclastic boneresorption. Defects in CBL are the cause of Noonan syndrome-like disorder with or without juvenilemyelomonocytic leukemia (NSLL) .
Product Name Alternative
Anti-CBL antibody, anti-E3 ubiquitinprotein ligase CBL antibody, anti-Casitas Blineage lymphoma protooncogene antibody, anti-Protooncogene cCbl antibody, anti- RING finger protein 55 antibody, anti-Signal transduction protein CBL antibody, anti-CBL2 antibody, anti-RNF55 antibody
UniProt
P22681
Reactivity
Human
Immunogen
C-terminal region of human CBL
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
100
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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