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APOBEC3g (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210226Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210226Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to APOBEC3 gamma.DNA dC-dU-editing enzyme APOBEC-3G (APOBEC3G) belongs to the cytidine and deoxycytidylatedeaminase family. It is a DNA deaminase (cytidine deaminase) that mediates a form of innateresistance to retroviral infections (at least to HIV-1 infection) by triggering G-to-A hypermutation in thenewly synthesized viral DNA. The inhibition of viral replication is either due to the degradation of theminus strand before its integration or to the lethality of the hypermutations. APOBEC3G also inhibitsthe infectivity of retroviral particles only distantly related to HIV-1, such as the simianimmunodeficiency virus (SIV), the equine infectious anemia virus (EIAV) and the murine leukemiavirus (MLV) .
Product Name Alternative
Anti-APOBEC3 gamma antibody, anti-DNA dCGreater than dUediting enzyme APOBEC3G antibody, anti-APOBECrelated cytidine deaminase antibody, anti-APOBECrelated protein antibody, anti-ARCD antibody, anti-APOBECrelated protein 9 antibody, anti-ARP9 antibody, anti-CEM15 antibody, anti-CEM15 antibody
UniProt
Q9HC16
Reactivity
Human
Immunogen
N-terminal region of human APOBEC3G
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology
Dilution
WB:1:500-1:1000
Purity
Affinity purification
Molecular Weight
46
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9HC16

DNA dC->dU-editing enzyme APOBEC-3G

ABC3G_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HC16
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APOBEC3G
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.5.4.38
Processing
—
Secondary accessions
B2RDR9, Q45F02, Q5TF77, Q7Z2N1, Q7Z2N4, Q9H9H8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseHost-virus interactionImmunityInnate immunity

Cellular component

CytoplasmNucleus

Molecular function

Hydrolase

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Domain

Repeat

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