Products for Research Use Only
RegisterLogin

DKK1 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210204Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18210204Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Rabbit polyclonal to DKK1.Dickkopf-related protein 1 (DKK1) belongs to the dickkopf family. DKK1 is a secreted protein thatinduces anterior development by antagonizing canonical Wnt signaling upstream of its effect on betacateninregulation. DKK1 inhibits LRP5/6 interaction with Wnt and by forming a ternary complex withthe transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play animportant role in vertebrate development, where they locally inhibit Wnt regulated processes such asantero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Product Name Alternative
Anti-DKK1 antibody, anti-Dickkopfrelated protein 1 antibody, anti-Dickkopf1 antibody, anti-Dkk1 antibody, anti-hDkk1 antibody, anti-SK antibody
UniProt
O94907
Reactivity
Human
Immunogen
N-terminal region of human DKK1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Dilution
WB:1:500-1:1000
Purity
Affinity purification
Molecular Weight
27
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · O94907

Dickkopf-related protein 1

DKK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O94907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DKK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dickkopf-1, Dkk-1, hDkk-1
EC number
—
Processing
Precursor
Secondary accessions
B2RC19
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Developmental protein

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

Biological process

Wnt signaling pathway

Related Products

CatalogName
GTR18087859Dkk1 Rabbit Polyclonal Antibody
GTR17871160DKK1 Rabbit Polyclonal Antibody
GTR18112340-01DKK1 Rabbit Polyclonal Antibody
GTR17723459-01DKK1 Rabbit Polyclonal Antibody
GTR17690137DKK1 Rabbit Polyclonal Antibody
GTR17873493DKK1 Rabbit Polyclonal Antibody
GTR18680694-01DKK1 Rabbit Polyclonal Antibody
GTR18684675-01DKK1 Rabbit Polyclonal Antibody
GTR18032898-01DKK1 Rabbit Polyclonal Antibody
GTR18091550DKK1 Rabbit Polyclonal Antibody

Alternative Products

CatalogName
E10G07254DKK1 Rabbit Polyclonal Antibody
MBS8101473-01Anti-DKK1 Antibody, Rabbit Polyclonal
TA351888Rabbit Polyclonal Anti-DKK1 Antibody
MBS668158-01DKK1 Polyclonal Antibody
APR00214GPolyclonal DKK1 Antibody
MBS240036-01Rabbit Polyclonal to Human DKK1

Popular Products