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KLRG1 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210084Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210084Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to KLRG1.Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a single-pass type II cell membraneprotein that is expressed specifically on natural killer (NK) cells and activated CD8 T-cells and isinduced by pathogens and viral infections. KLRG1 forms monomer and disulfide-linked homodimer.KLRG1 plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to theirnon-MHC ligands. KLRG1 may mediate missing self recognition by binding to a highly conserved siteon classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 andR-cadherin/CDH4 on target cells.
Product Name Alternative
Anti-KLRG1 antibody, anti-Killer cell lectinlike receptor subfamily G member 1 antibody, anti-Mast cell functionassociated antigen 2F1 antibody, anti-Mafa antibody
UniProt
O88713
Reactivity
Human, Mouse
Immunogen
C-terminal region of mouse KLRG1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
21
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · O88713

Killer cell lectin-like receptor subfamily G member 1

KLRG1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
O88713
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Klrg1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q3T1F0
Protein keywords

Technical term

3D-structureReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

ImmunityInnate immunity

Ligand

Lectin

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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