Products for Research Use Only

KDM3A (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210056Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210056Size:100 µL
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Description
Rabbit polyclonal to KDM3A.Lysine-specific histone demethylase 3A (KDM3A) is a histone demethylase that specificallydemethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. KDM3Apreferentially demethylates mono-and dimethylated H3 'Lys-9' residue, with a preference fordimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. KDM3A is involvedin hormone-dependent transcriptional activation, by participating in recruient to androgen-receptortarget genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. KDM3A has beenimplicated in spermatogenesis by regulating expression of target genes such as PRM1 and P1, which are required for packaging and condensation of sperm chromatin. KDM3A is also involved inobesity resistance through regulation of metabolic genes such as PPARA and UCP1.
Product Name Alternative
Anti-KDM3A antibody, anti-Lysinespecific demethylase 3A antibody, anti-JmjC domaincontaining histone demethylation protein 2A antibody, anti-Jumonji domaincontaining protein 1A antibody, anti-JHDM2A antibody, anti-JMJD1 antibody, anti-JMJD1A antibody, anti-KIAA0742 antibody, anti-TSGA antibody
UniProt
Q9Y4C1
Reactivity
Human
Immunogen
N-terminal region of human KDM3A
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
147
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9Y4C1

Lysine-specific demethylase 3A

KDM3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y4C1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDM3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.11.65
Processing
—
Secondary accessions
D6W5M3, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08
Protein keywords

PTM

AcetylationPhosphoprotein

Molecular function

ActivatorChromatin regulatorDioxygenaseOxidoreductase

Cellular component

CytoplasmNucleus

Biological process

DifferentiationSpermatogenesisTranscriptionTranscription regulation

Ligand

IronMetal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

Zinc-finger