KDM6A (N2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210036Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18210036Size:100 µL

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Description

Rabbit polyclonal to KDM6A.Lysine-specific demethylase 6A (KDM6A) is a histone demethylase that specifically demethylates'Lys-27' of histone H3, thereby playing a central role in histone code. KDM6A can demethylatetrimethylated and dimethylated but not monomethylated H3 'Lys-27', and it plays a central role in theregulation of posterior development by regulating HOX gene expression. KDM6A also regulates therecruient of the PRC1 complex and monoubiquitination of histone H2A.

Product Name Alternative

Anti-KDM6A antibody, anti-Lysinespecific demethylase 6A antibody, anti-Histone demethylase UTX antibody, anti-Ubiquitouslytranscribed TPR protein on the X chromosome antibody, anti-Ubiquitouslytranscribed X chromosome tetratricopeptide repeat protein antibody, anti-UTX antibody

UniProt

O15550

Reactivity

Human

Immunogen

N-terminal region of human KDM6A

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Metabolism Research

Dilution

WB:1:1000-1:5000

Purity

Affinity purification

Molecular Weight

154

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

Host or Source

Rabbit

Preservative

0.01% NaN3

UniProtKB · O15550

Lysine-specific demethylase 6A

KDM6A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O15550
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: KDM6A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 1.14.11.68
Processing: —
Secondary accessions: Q52LL9, Q5JVQ7

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Chromatin regulatorDioxygenaseOxidoreductase

Disease

Intellectual disability

Ligand

IronMetal-bindingZinc

PTM

MethylationPhosphoprotein

Cellular component

Nucleus

Domain

RepeatTPR repeat

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