Products for Research Use Only

KDM1B (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210027Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210027Size:100 µL
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Description
Rabbit polyclonal to KDM1B.Lysine-specific histone demethylase 1B (KDM1B) belongs to the flavin monoamine oxidase family.KDM1B is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetictranscriptional activation, thereby acting as a corepressor. KDM1B is required for de novo DNAmethylation of a subset of imprinted genes during oogenesis. KDM1B demethylates both mono-anddi-methylated 'Lys-4' of histone H3, but has no effect on tri-methylated 'Lys-4' or other methylated Lysresidues of histone H3 or H4.
Product Name Alternative
Anti-KDM1B antibody, anti-Lysinespecific histone demethylase 1B antibody, anti-Flavincontaining amine oxidase domaincontaining protein 1 Lysinespecific histone demethylase 2 antibody, anti-AOF1 antibody, anti-C6orf193 antibody, anti-LSD2 antibody
UniProt
Q8NB78
Reactivity
Human
Immunogen
N-terminal region of human KDM1B
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
92
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ChIP, IP, WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q8NB78

Lysine-specific histone demethylase 2

KDM1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NB78
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDM1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.99.66
Processing
—
Secondary accessions
A2A2C5, A2A2C6, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDevelopmental proteinOxidoreductaseRepressor

Cellular component

ChromosomeNucleus

Ligand

FADFlavoproteinMetal-bindingZinc

PTM

Phosphoprotein

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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