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RBBP8 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18209994Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18209994Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to RBBP8.RBBP8 is a DNA endonuclease that cooperates with the MRN complex in processing meiotic andmitotic double-strand breaks by ensuring both resection and intrachromosomal association of thebroken ends. RBBP8 promotes ATR and RPA recruient to DSBs in S/G2 phase and facilitates thegeneration of ssDNA. RBBP8 may modulate the functions ascribed to BRCA1 in transcriptionalregulation, DNA repair, and/or cell cycle checkpoint control.
Product Name Alternative
Anti-RBBP8 antibody, anti-CTIP antibody, anti-DNA endonuclease RBBP8 antibody, anti-CtBPinteracting protein antibody, anti-CtIP antibody, anti-Retinoblastomabinding protein 8 antibody, anti- RBBP8 antibody, anti-Retinoblastomainteracting protein and myosinlike antibody, anti-RIM antibody, anti-Sporulation in the absence of SPO11 protein 2 homolog antibody, anti-SAE2 antibody
UniProt
Q99708
Reactivity
Human, Mouse
Immunogen
N-terminal region of human RBBP8
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
102
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q99708

DNA endonuclease RBBP8

CTIP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99708
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RBBP8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.-.-
Processing
—
Secondary accessions
A6NKN2, A8K8W6, E7ETY1, O75371, Q8NHQ3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionDNA damageDNA repairMeiosisMitosis

Cellular component

ChromosomeNucleus

Domain

Coiled coil

Disease

Disease variantDwarfismIntellectual disability

Molecular function

DNA-bindingEndonucleaseHydrolaseNuclease

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

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