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SMAD2 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18209597Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18209597Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to SMAD2.SMAD2 is a transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase.SMAD2 is a receptor-regulated SMAD -SMAD) . SMAD2 is phosphorylated by the activated receptorkinase upon ligand stimulation, and forms a complex with other SMADs. The SMAD complex thentranslocates into the nucleus to regulate transcription. SMAD2 may act as a tumor suppressor incolorectal carcinoma.
Product Name Alternative
Anti-SMAD2 antibody, anti-JV18 antibody, anti-JV181 antibody, anti-MADH2 antibody, anti-MADR2 antibody, anti-MGC22139 antibody, anti-MGC34440 antibody, anti-hMAD2 antibody, anti-Hsmad2 antibody
UniProt
Q15796
Reactivity
Human, Mouse
Immunogen
N-terminal region of human SMADs
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
52
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q15796

SMAD family member 2

SMAD2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15796
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMAD2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SMAD 2, hSMAD2
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Disease

Disease variantHeterotaxy

Molecular function

DNA-binding

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulation

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