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Trovirdine

CAT: 0804-HY-15349-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15349-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA) and dGTP as substrate. IC50 value: 7 nM Target: HIV-1 Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.
CAS Number
149488-17-5
Product Name Alternative
LY300046
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Trovirdine.html
Purity
99.43
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=C(NCCC1=NC=CC=C1)NC2=NC=C(Br)C=C2
Molecular Formula
C13H13BrN4S
Molecular Weight
337.24
Precautions
H315, H319, H335
References & Citations
[1]Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127.|[2]Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
HIV-1

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CatalogName
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MBS5781329Trovirdine hydrochloride
A13199-100Trovirdine 100mg
A13199-50Trovirdine 50mg
A13199-25Trovirdine 25mg
A13199-10Trovirdine 10mg
A13199-5Trovirdine 5mg
A13199-2Trovirdine 2mg
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A13199-10mM-DTrovirdine 10mM * 1mL in DMSO

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