Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
CAT:
804-HY-21577-02
Size:
250 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
- CAS Number: 175724-30-8
- UNSPSC Description: Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- Target Antigen: ADC Linker; PROTAC Linkers
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tris-2-tert-butoxycarbonyl-ethoxy-methyl-methylamine.html
- Purity: 98.0
- Solubility: DMSO : 175 mg/mL (ultrasonic)
- Smiles: O=C(OC(C)(C)C)CCOCC(COCCC(OC(C)(C)C)=O)(N)COCCC(OC(C)(C)C)=O
- Molecular Weight: 505.64
- References & Citations: [1]Kostiainen MA, et al. Optically degradable dendrons for temporary adhesion of proteins to DNA. Chemistry. 2010 Jun 18;16(23):6912-8.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported