Pentapeptide-3

• Description:

  Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides[1][2].

• UNSPSC:

  12352209

• Hazard Statement:

  H302

• Target:

  NAChR

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pentapeptide-3.html

• Purity:

  99.73

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C([C@H]1N(CCC1)C(CN)=O)N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N)=O)=O)=O

• Molecular Formula:

  C21H37N9O5

• Molecular Weight:

  495.58

• Precautions:

  H302

• References & Citations:

  [1]Schagen, S.K. Topical peptide treatments with effective anti-aging results. Cosmetics 4 (2), 2017.|[2]Zhmak MN, et al. Peptide inhibitors of nicotinic acetylcholine receptor. WO2014/112902Al, 2017.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [135679-88-8]