(Z) -Azoxystrobin

• Description :

  (Z) -Azoxystrobin is an enantiomer of Azoxystrobin. Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1][2][3][4].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Apoptosis; Bacterial; Fungal; Phosphatase; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/z-azoxystrobin.html

• Smiles :

  CO/C=C(C1=C(OC2=NC=NC(OC3=C(C=CC=C3)C#N)=C2)C=CC=C1)/C(OC)=O

• Molecular Formula :

  C22H17N3O5

• Molecular Weight :

  403.39

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Enock Mpofu, et al. Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. Chemosphere. 2021 Jun;273:129663.|[2]Bertelsen, J.R, et al. Fungicidal effects of azoxystrobin and epoxiconazole on phyllosphere fungi, senescence and yield of winter wheat. Plant Pathology, 50: 190-205.|[3]Wang X, et al. Fungicide azoxystrobin induced changes on the soil microbiome[J]. Applied Soil Ecology, 2020, 145: 103343.|[4]Zhang Q, et al. Oral azoxystrobin driving the dynamic change in resistome by disturbing the stability of the gut microbiota of Enchytraeus crypticus. J Hazard Mater. 2022 Feb 5;423 (Pt B) :127252.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [143130-94-3]