(Z) -Azoxystrobin

CAT: 0804-HY-B0849A-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0849A-01Size:1 mg
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Description
(Z) -Azoxystrobin is an enantiomer of Azoxystrobin. Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1][2][3][4].
CAS Number
[143130-94-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Bacterial; Fungal; Phosphatase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/z-azoxystrobin.html
Smiles
CO/C=C(C1=C(OC2=NC=NC(OC3=C(C=CC=C3)C#N)=C2)C=CC=C1)/C(OC)=O
Molecular Formula
C22H17N3O5
Molecular Weight
403.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Enock Mpofu, et al. Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. Chemosphere. 2021 Jun;273:129663.|[2]Bertelsen, J.R, et al. Fungicidal effects of azoxystrobin and epoxiconazole on phyllosphere fungi, senescence and yield of winter wheat. Plant Pathology, 50: 190-205.|[3]Wang X, et al. Fungicide azoxystrobin induced changes on the soil microbiome[J]. Applied Soil Ecology, 2020, 145: 103343.|[4]Zhang Q, et al. Oral azoxystrobin driving the dynamic change in resistome by disturbing the stability of the gut microbiota of Enchytraeus crypticus. J Hazard Mater. 2022 Feb 5;423 (Pt B) :127252.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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