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PKM2 Antibody

CAT: 0013-GTR18206965-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18206965-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Monoclonal antibody to PKM2.Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.
Product Name Alternative
Pyruvate kinase isozymes M1/M2, EC 2.7.1.40, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, M2PK, PKM2, PK3, PK2, PKM, TCB, OIP3, MGC3932, Tumor Type M2 Pyruvate Kinase.
Reactivity
Human
Immunogen
Anti-human PKM2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PKM2 amino acids 1-531 purified from E. coli
Clonality
Monoclonal
Clone
PAT1B10AT
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
PKM2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Applications: PKM2 antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results
Host or Source
Mouse
Preservative
1mg/ml containing PBS, pH-7.4, & 0.02% Sodium Azide and 10% glycerol.
Isotype
Mouse IgG1 heavy chain and κ light chain

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