Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

• CAS Number: 1926163-65-6
• UNSPSC Description: Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy[1].
• Target Antigen: Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Field of Research: others
• Assay Protocol: https://www.medchemexpress.com/fluorescein-6-carbonyl-asp-ome-glu-ome-val-dl-asp-ome-fluoromethylketone.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC(C(N[C@@H](CC(OC)=O)C(N[C@@H](CCC(OC)=O)C(N[C@@H](C(C)C)C(NC(C(CF)=O)CC(OC)=O)=O)=O)=O)=O)=CC=C51
• Molecular Weight: 892.83
• References & Citations: [1]M Kalai, et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ. 2002 Sep;9(9):981-94.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported