Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

• UNSPSC Description:

  Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/fluorescein-6-carbonyl-asp-ome-glu-ome-val-dl-asp-ome-fluoromethylketone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC(C(N[C@@H](CC(OC)=O)C(N[C@@H](CCC(OC)=O)C(N[C@@H](C(C)C)C(NC(C(CF)=O)CC(OC)=O)=O)=O)=O)=O)=CC=C51

• Molecular Weight:

  892.83

• References & Citations:

  [1]M Kalai, et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ. 2002 Sep;9(9):981-94.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1926163-65-6