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Cathepsin D Antibody

CAT: 0013-GTR18207212-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18207212-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Product Name Alternative
Ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.
Reactivity
Canine, Human, Monkey, Mouse, Rat
Immunogen
Antigen: Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli. Antigen Sequence: DQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL
Target
Cathepsin D
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Epitope affinity purified
Concentration
Please inquire
Dilution
WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000, IEM:1:50-1:200
Form
Polyclonal antibody supplied as a 200 or 500 μl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
References & Citations
Feng, Xu et al. Genome-wide differential expression profiling of mRNAs and lncRNAs associated with prolificacy in Hu sheep Biosci Rep, 38, (2018)
Pubmed id
29439142
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The antibody solution should be gently mixed before use.
Tested Applications
IEM, IF, IHC-Fr, IHC-P, WB
Host or Source
Goat
Isotype
IgG

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