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CARM1 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210073Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210073Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to CARM1.Coactivator-associated arginine methyltransferase 1 (CARM1) is also known as Protein arginine Nmethyltransferase4 (PRMT4), which catalyze the transfer of a methyl group from S-adenosyl-Lmethionineto the side chain nitrogens of arginine residues within proteins to form methylated argininederivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated insignal transduction, metabolism of nascent pre-RNA, and transcriptional activation Methylates (monoandasymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involvedin DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. CARM1 isrecruited to promoters upon gene activation together with histone acetyltransferases fromEP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainlyasymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling.
Product Name Alternative
Anti-CARM1 antibody, anti-Histonearginine methyltransferase CARM1 antibody, anti-Coactivatorassociated arginine methyltransferase 1 antibody, anti- Protein arginine Nmethyltransferase 4 antibody, anti-PRMT4 antibody
UniProt
Q86X55
Reactivity
Human, Mouse
Immunogen
C-terminal region of human CARM1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
66
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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