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KDM5C (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210049Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210049Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to KDM5C.Lysine-specific demethylase 5C (KDM5C) is a histone demethylase that specifically demethylates'Lys-4' of histone H3, thereby playing a central role in histone code. KDM5C does not demethylatehistone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. KDM5C demethylatestrimethylated and dimethylated but not monomethylated H3 'Lys-4'. KDM5C has been shown toparticipate in transcriptional repression of neuronal genes by recruiting histone deacetylases andREST at neuron-restrictive silencer elements.
Product Name Alternative
Anti-KDM5C antibody, anti-Lysinespecific demethylase 5C antibody, anti-Histone demethylase JARID1C antibody, anti-Jumonji antibody, anti-ARID domaincontaining protein 1C antibody, anti-Protein SmcX antibody, anti-Protein Xe169 antibody, anti-DXS1272E antibody, anti-JARID1C antibody, anti-SMCX antibody, anti-XE169 antibody
UniProt
P41229
Reactivity
Human
Immunogen
N-terminal region of human KDM5C
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
176
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · P41229

Lysine-specific demethylase 5C

KDM5C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P41229
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDM5C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.11.67
Processing
—
Secondary accessions
B0QZ44, B4E3I2, F5H3T1, Q5JUX3, Q5JUX4, Q5JUX5, Q7Z5S5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsTranscriptionTranscription regulation

Molecular function

Chromatin regulatorDioxygenaseOxidoreductaseRepressor

Disease

Disease variantIntellectual disability

Ligand

IronMetal-bindingZinc

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Domain

RepeatZinc-finger

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