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LDHA Antibody

CAT: 0013-GTR18206999-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18206999-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Monoclonal antibody to LDHA.LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential.
Product Name Alternative
LDH-A, GSD11, LDH1, LDHM, PIG19, EC 1.1.1.27, lactate dehydrogenase M, LDH-M, LDH-1, L-lactate dehydrogenase A chain, LDH muscle subunit, Renal carcinoma antigen NY-REN-59, Cell proliferation-inducing gene 19 protein, LDHA.
Reactivity
Human
Immunogen
Anti-human LDHA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LDHA amino acids 1-332 purified from E. coli
Clonality
Monoclonal
Clone
PAT1A4AT
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
LDHA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Applications: LDHA antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:500 ~ 8,000.Recommended starting dilution is 1:1,000
Host or Source
Mouse
Preservative
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Isotype
Mouse IgG2b heavy chain and κ light chain

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