IL-13 receptor alpha 2 Recombinant Rabbit Monoclonal Antibody [PSH03-85]

IL-13 receptor alpha 2 Recombinant Rabbit Monoclonal Antibody [PSH03-85]

• Description: Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene. IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however, able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13. IL-13Rα2 has been found to be over-expressed in a variety of cancers, including pancreatic, ovarian, melanomas, and malignant gliomas.
• Product Name Alternative: Cancer/testis antigen 19 antibody CD213a2 antibody CT19 antibody I13R2_HUMAN antibody IL-13 receptor subunit alpha-2 antibody IL-13R subunit alpha-2 antibody IL-13R-alpha-2 antibody IL-13RA2 antibody IL13 receptor antibody IL13BP antibody IL13R antibody Il13ra2 antibody Interleukin 13 binding protein antibody Interleukin 13 receptor alpha 2 chain antibody Interleukin-13 receptor subunit alpha-2 antibody Interleukin-13-binding protein antibody
• Abbreviation: IL13RA2, IL13R
• CAS Number: 9000-83-3
• Swiss Prot: Q14627 Human
• Cellular Locus: Membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within human IL-13 receptor alpha 2 aa 1-350 / 380.
• Isotype: IgG
• Clone: PSH03-85
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: A375 cell lysate, U-87 MG cell lysates, human testis tissue, A375.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:1,000 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 44 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes