Avanafil-d4

• Description :

  Avanafil-d4 (TA1790-d4) is deuterium-labeled Avanafil (HY-18252) [1].

• CAS Number :

  [2012598-68-2]

• Product Name Alternative :

  TA1790-d4

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite; Isotope-Labeled Compounds; NO Synthase; Phosphodiesterase (PDE)

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Smiles :

  COC1=C(Cl)C=C(CNC2=C(C(NCC3=NC=CC=N3)=O)C=NC(N4[C@H](C([2H])([2H])O)CCC4([2H])[2H])=N2)C=C1

• Molecular Formula :

  C23H22D4ClN7O3

• Molecular Weight :

  487.98

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Smith K A, et al. Soil and environmental analysis[M]. Marcel Dekker Incorporated, 2000.|[3]Fan T W M, et al. Stable isotope-resolved metabolomics and applications for drug development[J]. Pharmacology & therapeutics, 2012, 133 (3) : 366-391.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported