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Khellin (Standard)

CAT: 0804-HY-B1394R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1394R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Khellin (Standard) is the analytical standard of Khellin. This product is intended for research and analytical applications. Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].
CAS Number
82-02-0
UNSPSC
12352005
Target
EGFR; Reference Standards
Type
Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/khellin-standard.html
Smiles
O=C1C=C(C)OC2=C(OC)C(OC=C3)=C3C(OC)=C12
Molecular Formula
C14H12O5
Molecular Weight
260.24
References & Citations
[1]Abdel-Sattar S Hamad Elgazwy, et al. Molecular modeling study bioactive natural product of khellin analogues as a novel potential pharmacophore of EGFR inhibitors. J Enzyme Inhib Med Chem. 2013 Dec;28 (6) :1171-81.|[2]A Ubeda, et al. Relaxant actions of khellin on vascular smooth muscle. J Pharm Pharmacol . 1989 Apr;41 (4) :236-41.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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