Ebselen

• Background :

  Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro) /3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19

• Type :

  Chemical

• Purity :

  Greater than or equal to 98% (HPLC)

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.

• Calculated Molecular Weight :

  274.2

• Other Product Names :

  2-Phenyl-1,2-benzisoselenazol-3- (2H) -one

• Physical Properties :

  Lyophilized

• CAS Number :

  60940-34-3