NOX2 Peptide

• NCBI Gene ID:

  1536

• Swiss Prot:

  P04839

• Accession Number:

  NP_000388

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store NOX2 Peptide at -20˚ C, stable for one year.

• Applications Notes:

  The peptide is used for blocking the activity of NOX2 Antibody (catalog number 7923) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

• NCBI Official Name:

  Cytochrome b-245, beta polypeptide

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bedard K and Krause KH. The Nox family of ROS-generating NAPDH oxidases: physiology and pathophysiology. Physiol. Rev. 2007; 87:245-313.

• Background Reference 02:

  Segal AW. Cytochrome b-245 and its involvement in the molecular pathology of chronic granulomatous disease. Hematol. Oncol. North Am. 1988; 2:213-23.

• Background Reference 03:

  Surace MJ and Block ML. Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cell Mol. Life Sci. 2012; 69:2409-27.

• Other Product Names:

  CGD, NOX2, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b558 subunit beta

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  6996021

• Physical Properties:

  Liquid