Reproterol (hydrochloride)

Reproterol (hydrochloride)

• CAS Number: 13055-82-8
• UNSPSC Description: Reproterol hydrochloride is a dual-acting beta2-adrenoceptor agonist and phosphodiesterase inhibitor. Reproterol hydrochloride is more potent than albuterol and feterol in stimulating cAMP production in human monocytes, demonstrating its potential in enhancing airway function. Furthermore, Reproterol significantly inhibited the production of LTB4, indicating its anti-inflammatory properties. Reproterol hydrochloride may have inhibitory effects in respiratory diseases such as asthma and COPD[1].
• Target Antigen: Adrenergic Receptor; Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/reproterol-hydrochloride.html
• Smiles: O=C(N1C)N(C)C2=C(N(CCCNCC(C3=CC(O)=CC(O)=C3)O)C=N2)C1=O.Cl
• Molecular Weight: 425.87
• References & Citations: [1]Juergens UR, et al. Different mechanisms of action of beta2-adrenergic receptor agonists: a comparison of reproterol, fenoterol and salbutamol on monocyte cyclic-AMP and leukotriene B4 production in vitro. Eur J Med Res. 2004 Jul 30;9(7):365-70.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported