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H-Pro-Met-OH

CAT: 0804-HY-P4559Size: 1 EachDry Ice: NoHazardous: No
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Description
H-Pro-Met-OH is a dipeptide containing proline and methionine, which can serve as a substrate for prolinase. H-Pro-Met-OH can also be used for the synthesis of polypeptides[1][2].
CAS Number
52899-08-8
UNSPSC
12352209
Target
Dipeptidyl Peptidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-pro-met-oh.html
Solubility
10 mM in DMSO
Smiles
CSCC[C@@H](C(O)=O)NC([C@@H]1CCCN1)=O
Molecular Formula
C10H18N2O3S
Molecular Weight
246.33
References & Citations
[1]Maes W, et al. Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells. Regul Pept. 2004 Apr 15;118 (1-2) :105-9.|[2]Uramatsu M, et al. Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes. Clin Chim Acta. 2007 Jan;375 (1-2) :129-35.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Chemical Information

Pro-Met

Pro-Met is a dipeptide obtained by formal condensation of the carboxy group of L-proline with the amino group of L-methionine. It is functionally related to a L-methionine and a L-proline.

CAS Number52899-08-8
PubChem CID7408173
IUPAC Name(2S)-4-methylsulfanyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoic acid
Molecular FormulaC10H18N2O3S
Molecular Weight246.33
XLogP-3.1
Topological Polar Surface Area104
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count16
Formal Charge0
Complexity260
SMILES
CSCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1
InChI
InChI=1S/C10H18N2O3S/c1-16-6-4-8(10(14)15)12-9(13)7-3-2-5-11-7/h7-8,11H,2-6H2,1H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1
InChIKey
MTWJTFBVRDGROD-YUMQZZPRSA-N
Chemical Structure
2D Structure
2D structure of Pro-Met
CAS: 52899-08-8
CID: 7408173
Formula: C10H18N2O3S
MW: 246.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight246.33
XLogP3-3.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass246.10381361
Monoisotopic Mass246.10381361
Topological Polar Surface Area104 Ų
Heavy Atom Count16
Formal Charge0
Complexity260
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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G-3045.0001H-Pro-Met-OH
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