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Tolmesoxide

CAT: 0804-HY-107037Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107037Size:1 Each
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Description
Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina[1].
CAS Number
38452-29-8
Product Name Alternative
RX71107
UNSPSC
12352005
Target
Adrenergic Receptor; Angiotensin Receptor; Vasopressin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tolmesoxide.html
Smiles
CS(C1=C(C=C(OC)C(OC)=C1)C)=O
Molecular Formula
C10H14O3S
Molecular Weight
214.28
References & Citations
[1]Collier J G, et al. Comparison of effects of tolmesoxide (RX71107), diazoxide, hydrallazine, prazosin, glyceryl trinitrate and sodium nitroprusside on forearm arteries and dorsal hand veins of man[J]. British journal of clinical pharmacology, 1978, 5 (1) : 35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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