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Tigar Recombinant Protein

CAT: 0223-40-661Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0223-40-661Size:5 µg
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Background
TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant Human TIGAR expressed in E. coli is a 29.9 kDa protein containing 269 amino acid residues.
CAS Number
9000-83-3
NCBI Gene ID
57103
Swiss Prot
Q9NQ88
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Stem Cell, Apoptosis, Cancer
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
TP53 induced glycolysis regulatory phosphatase
NCBI Organism
Homo sapiens
Other Product Names
TP53-induced glycolysis and apoptosis regulator (TIGAR)
Species
Human
Physical Properties
Lyophilized

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