SARS-CoV-2 (COVID-19) Envelope Recombinant Protein

• Background:

  These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.

• NCBI Gene ID:

  43740570

• Swiss Prot:

  QHD43418.1

• Accession Number:

  QHD43418.1

• Tag:

  N-BBP-6His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Infectious Disease, COVID-19

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE.

• Buffer:

  Supplied as a 0.2 uM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Reconstituted protein solution should be store below -20˚ C.

• Calculated Molecular Weight:

  27.5kDa, 22-25kDa

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Envelope protein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Other Product Names:

  2019-nCoV E protein; 2019-nCoV sM protein

• Species:

  SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Protein

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3