Products for Research Use Only
RegisterLogin

IFN alpha Recombinant Protein

CAT: 0223-91-329Size: 0.05 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-91-329Size:0.05 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The Interferon- alpha/ beta Receptor 1 (IFN- alpha/ beta R1) is a receptor which binds Type I Interferons including Interferon- alpha and - beta . It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. IFN- alpha/ beta R1, in association with IFN- alpha/ beta R2, is required for propagating antiviral signal transduction triggered by IFN- alpha and IFN- beta . IFN- alpha/ beta R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN- alpha/ beta R2. Ligands associate with IFN- alpha/ beta R2, and this complex subsequently forms a stable ternary assembly with IFN- alpha/ beta R1. IFN- alpha/ beta R1 also associates with IFN- gamma R2 even in the absence of IFN- gamma stimulation. Human IFN- alpha/ beta R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand. Interferon stimulation results in an immunologic response that is especially associated with viruses.
CAS Number
9000-83-3
NCBI Gene ID
3454
Swiss Prot
P17181
Accession Number
P17181
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Immunology, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
48.18 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interferon alpha and beta receptor subunit 1
NCBI Organism
Homo sapiens
Other Product Names
Interferon Alpha/Beta Receptor 1, IFN-R-1, IFN-Alpha/Beta Receptor 1, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, Type I Interferon Receptor 1, IFNAR1, IFNAR, beta R1
Species
Human
Protein ID
530394832
Physical Properties
Lyophilized

Related Products

CatalogName
91-559IFN alpha-6 Recombinant Protein
91-018IFN alpha-2a Recombinant Protein
92-577IFN alpha-2 Recombinant Protein
11-192IFN-alpha 1 Recombinant Protein
91-853IFN alpha-1 Recombinant Protein
91-004IFN alpha-2b Recombinant Protein
11-193IFN-alpha 1 Recombinant Protein
91-822IFN alpha-4 Recombinant Protein
30-008Interferon (IFN) alpha 2A Recombinant Protein
92-633IFN gamma Recombinant Protein

Alternative Products

CatalogName
MBS515368-01HSP90 alpha recombinant protein
MBS515365-01Catenin alpha recombinant protein
OPCA02121-1MGAlpha-trichosanthin Recombinant Protein
GTR18911764-01SCGF alpha Recombinant Protein
GTR18909423SNAP-alpha Recombinant Protein
GTR18909419TNF-alpha Recombinant Protein
GTR18908722TNF alpha Recombinant Protein
GTR18910407Reg1 alpha Recombinant Protein
GTR18909852Alpha-Parvin Recombinant Protein
GTR18909788Alpha-Synuclein Recombinant Protein

Popular Products