Serpin H1 Recombinant Protein

• Background:

  Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.

• NCBI Gene ID:

  871

• Swiss Prot:

  P50454

• Accession Number:

  P50454

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cell Cycle, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  45.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Serpin H1, 47 kDa Heat Shock Protein, Arsenic-Transactivated Protein 3, AsTP3, Cell Proliferation-Inducing Gene 14 Protein, Collagen-Binding Protein, Colligin, Rheumatoid Arthritis-Related Antigen RA-A47, SERPINH1, CBP1, CBP2, HSP47, SERPINH2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3