Sentrin-Specific Protease 7 Recombinant Protein

CAT: 0223-91-151Size: 0.05 mgDry Ice: YesHazardous: No
CAT#:0223-91-151Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
CAS Number
9000-83-3
NCBI Gene ID
57337
Swiss Prot
Q9BQF6
Accession Number
Q9BQF6
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle
Buffer
Supplied as a 0.2 um filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
27.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
SUMO1/sentrin specific peptidase 7
NCBI Organism
Homo sapiens
Other Product Names
Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2
Species
Human
Physical Properties
Liquid

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