Semaphorin 4C Recombinant Protein

• Background:

  Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

• NCBI Gene ID:

  20353

• Swiss Prot:

  Q64151

• Accession Number:

  Q64151

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  99.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Semaphorin-4C, Semaphorin I, S4c, Semacl1, Semai, Sema I, Semaphorin-C-like 1, M-Sema F, Sema4c

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3