Products for Research Use Only
RegisterLogin

AKT1 Recombinant Protein

CAT: 0223-96-020Size: 0.025 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-96-020Size:0.025 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RAC-alpha serine/threonine-protein kinase (AKT1) is also known PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt and RAC-PK-alpha, which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and RAC subfamily and is expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level) . AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven. AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase) .
CAS Number
9000-83-3
NCBI Gene ID
207
Swiss Prot
P31749
Accession Number
AAH00479
Tag
C-His, C-Twin Strep Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Autophagy, Cancer, Neuroscience, Signal Transduction
Buffer
20 mM tris, 150 mM NaCl, pH8.0
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
59.5 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
V-akt murine thymoma viral oncogene homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Jones P.F., et al., 1991, Proc. Natl. Acad. Sci. U.S.A. 88:4171-4175.
Background Reference 02
Goshima N., et al., 2008 Nat. Methods 5:1011-1017.
Background Reference 03
Delcommenne M., et al ., 1998, Proc. Natl. Acad. Sci. U.S.A. 95:11211-11216.
Other Product Names
AKT1, PKB, RAC, RAC-PK-alpha, PKB alpha
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

Related Products

CatalogName
71-070AKT (AKT1/AKT2/AKT3) Antibody
79-417AKT1 / AKT2 / AKT3 (Ab 315 / 316 / 312) Antibody
79-238AKT1 / AKT2 / AKT3 (phospho Tyr315 / Tyr316 / Tyr312) Antibody
22-824AKT1 Antibody
3519-002mgAkt1 Antibody
3519PAkt1 Peptide
31-053AKT1 Antibody
XW-7019AKT1 Antibody
14-185AKT1 Antibody
3519-01mgAkt1 Antibody

Alternative Products

CatalogName
OPCD06207-10UGAKT1 Recombinant Protein
MBS389202-01Recombinant AKT1 protein
ATGP2915-100Recombinant human Akt1 protein
OPCA01087-1MGAKT1 Recombinant Protein (Human)
RP115250AKT1 Recombinant Protein (Mouse)
NBP2-52957PEPAKT1 Recombinant Protein Antigen
MBS515207-01AKT1, Unactive recombinant protein
PPT-10481Human AKT1 Recombinant Protein
RP189809AKT1 Recombinant Protein (Rat)
PROTP31749AKT1 (NM_001014432) Human Recombinant Protein

Popular Products