MHC Class I-related Protein A Recombinant Protein

• Background:

  MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains one Ig-like C1-type domain and is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA is the ligand for NK cell activating receptor KLRK1/NKG2D. MICA seems to have no role in antigen presentation. MICA leads to cell lysis by binding to KLRK1.

• NCBI Gene ID:

  100507436

• Swiss Prot:

  Q29983

• Accession Number:

  Q29983

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  59.9 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  MHC class I polypeptide-related sequence A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MHC Class I Polypeptide-Related Sequence A, MIC-A, MICA, PERB11.1

• Species:

  Human

• Protein ID:

  767928039

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3